Ketamine trial
Ketamine is a medication that was developed in the 1960s for use in anesthesia in human surgery. In the last few years, new uses for ketamine at doses much lower than needed for surgery have been found to have other benefits and show promise for treating chronic conditions that existing medications can’t. In humans, ketamine is given in low doses to treat severe depression, and recent studies in mice show promise in reducing chronic pain. This study will provide objective assessments of a treatment that is already used for pets with pain (however, without knowledge of whether the treatment works/benefits the patient). The treatment we are assessing in this trial is giving ketamine at a subanesthetic dose by transmucosal route to see how well it can treat pain associated with arthritis.
condition(s)
eligibility information
To participate in the trial, dogs must:
- Have radiographically confirmed osteoarthritis in affected elbow
- Be otherwise systemically healthy
- Have concomitant disease well controlled prior to enrollment
- Be amenable to objective gait analysis
- Be able to wear a collar
This study will take about 1 month, and participants should be able to attend at least 4 in-person appointments.
contact information
If you’re interested in enrolling in this trial, please email [email protected].
