Brad BorleeMicrobiology, Immunology, and Pathology
Dr. Borlee is an Associate Professor of Bacteriology and Boettcher Investigator in the Department of Microbiology, Immunology, and Pathology within the College of Veterinary Medicine and Biomedical Sciences. He was previously a Senior Fellow in the Department of Microbiology at the University of Washington, School of Medicine (Seattle, WA), and earned his Ph.D. conducting microbiology research at the University of Wisconsin (Madison, WI). Highlights of his research career include the pioneering construction of metagenomic libraries to study antibiotic resistance and identification of novel biomolecules from unculturable bacteria. In addition, Dr. Borlee has patented quorum-sensing inhibitors for the development of anti-virulence drug leads. Dr. Borlee’s discovery of a biofilm-induced bacterial adhesin that binds exopolysaccharides and reinforces biofilm structural integrity has been further developed by him into a c-di-GMP biosensor to identify and evaluate antibiofilm therapeutics.