The Prion Research Center is a leader in the study of prions, the causative agent of transmissible spongiform encephalopathies, which remains one of the most exciting and dynamic frontiers of biology. Built on established expertise, the center was founded in 2011 to further pioneer prion research and training at Colorado State University,
Our researchers investigate the biochemistry, genetics and pathogenesis of prions in mammals, as well as genetically tractable yeast systems. Growing evidence also links the prion mechanism to proteins involved in the pathogenesis of other common neurodegenerative diseases, including Alzheimer’s and Parkinson’s, and forms an emerging area of the center’s studies.
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The Atlantic: Deer Are Beta-Testing a Nightmare Disease
Candace Mathiason, a pathobiologist at Colorado State University, and her colleagues have found that as little as 100 nanograms of saliva can seed a chronic wasting disease infection. Her studies suggest that deer can also pass prions in utero from doe to growing fawn.
Drug Discovery News: Hope for Prion Diseases
While most researchers are focusing on the prions themselves, Julie Moreno, a molecular biologist at Colorado State University, thinks that targeting downstream effects presents another promising therapeutic approach.
Chronic Wasting Disease Research and Management
Hear from leading experts at CSU, the United States Department of Agriculture and the National Parks Service about how chronic wasting disease impacts cervid populations around the globe, and what we’ve learned about prion-related infectious agents
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