Candace Mathiason

Faculty Microbiology, Immunology, and Pathology

About Candace

Dr. Mathiason is Associate Professor of Pathobiology and Director of the Office of Vice President for Research (OVPR) Program for Research and Scholarly Excellence (PRSE)- Infectious Disease and Rapid Response Network. Dr. Mathiason’s research focuses on the role blood and maternal infections play in disease pathogenesis and transmission dynamics. Her laboratory combines use of native and rodent in vivo hosts with highly sensitive in vitro assays to assimilate an understanding of the biological mechanisms associated with covert transmission of infectious agents. The intent of these works is to provide basic science principles for continued efforts to mitigate infectious agents via preventative, therapeutic and vaccine therapies.

Education

BS, University of Wyoming, 1983MS, University of Wyoming, 1987PhD, Colorado State University, 2010

Publications

Nalls AV, McNulty E, Hoover CE, Pulscher LA, Hoover EA, Mathiason CK. Infectious Prions in the Pregnancy Microenvironment of CWD-infected Reeves' Muntjac Deer. 2017 J VirologyShikiya RA, Langenfeld KA, Eckland TE, Trinh J, Holec SA, Mathiason CK, Kincaid AE, Bartz JC. PrPSc formation and clearance as determinants of prion tropism. 2017 PLoS PathogensMathiason CK. Silent Prions and Covert Prion Transmission. 2015 PLoS PathogensSelariu A, Powers JG, Nalls A, Brandbuger M, Mayfield A, Fullaway S, Wyckoff CA, Zabel M, Wild MA, Hoover EA, Mathiason CK. In utero transmission and tissue distribution of chronic wasting disease-associated prions in free-ranging Rocky Mountain elk. 2015 J Gen VirologyElder A, Henderson DM, Nalls A, Kincaid A, Hoover EA, Bartz JC, Mathiason CK. Immediate and ongoing detection of prions in the blood of hamsters and deer following oral, nasal, or blood inoculations. 2015 J VirologyElder AM, Henderson DM, Nalls AV, Wilham JM, Caughey BW, Hoover EA, Kincaid AE, Bartz JC, Mathiason CK. In vitro detection of prionemia in TSE-infected cervids and hamsters. 2013 PLoS One Nalls AV, McNulty E, Powers J, Seelig DM, Hoover C, Haley NJ, Hayes-Klug J, Anderson K, Stewart P, Goldmann W, Hoover EA, Mathiason CK. Mother to offspring transmission of chronic wasting disease in reeves’ muntjac deer. 2013 PLoS One

Research Specialty

Cervids and rodents

                

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