GLP and non-GLP preclinical testing

Our team of board-certified veterinary surgeons and experienced staff are prepared to organize and perform studies encompassing a variety of orthopedic, soft tissue, and metabolic conditions. GLP studies are compliant with Good Laboratory Practice for Nonclinical Laboratory Studies (21 CFR Part 58) per the United States Food and Drug Administration. We also accommodate non-GLP pilot and pivotal studies.

In partnership with the Orthopaedic Bioengineering Research Laboratory, we offer a full suite of preclinical research services. In vivo services are provided by the Preclinical Surgical Research Laboratory and ex vivo services are offered by the Orthopaedic Bioengineering Research Laboratory.

Research Applications/Studies


  • Lumbar interbody fusion
  • Posterolateral intervertebral fusion
  • Cervical fusion
  • Vertebroplasty
  • Laminectomy


  • Bone healing studies
  • Internal fixation implant testing
  • External fixation implant testing
  • Allograft, autograft, and xenograft testing
  • Osteochondral defect/cartilage regeneration

Sports medicine

  • Anterior cruciate ligament and meniscus
  • Tendon and ligament reconstruction and healing
  • Rotator cuff
  • Arthroscopic surgery

Soft tissue

  • Wound reconstruction and healing
  • Urogenital implants
  • Laparoscopic surgery


  • Nutritional studies
  • Hormonal studies
  • Laparoscopic ovariectomy


  • Safety, efficacy, and pharmacokinetics
  • Pain management

Specialized Technology

woman looking at image of spine on screen

Housed within Colorado State University’s Translational Medicine Institute, our laboratory space is dedicated to providing GLP and non-GLP preclinical testing. Our in vivo services are made possible by a spectrum of leading-edge technologies, including:

  • Digital radiographic imaging
  • Computed tomography (CT) imaging
  • Fluoroscopy
  • Magnetic resonance imaging (MRI)
  • GLP-compliant in vivo imaging system (IVIS)
  • Dual-energy X-ray absorptiometry (DEXA)

Through our partnership with the Orthopaedic Bioengineering Research Laboratory, clients gain access to additional specialized technology for ex vivo services.