Scientific Global Talks

About

Featuring a vast network of investigators of translational medicine from around the world, Scientific Global Talks brings cutting edge research information to a global audience. Working collaboratively both within the Translational Medicine Institute as well as with many worldwide investigators, we are committed to our mission to improve the lives of animals and humans through biologic therapies, to expedite the availability of these therapies, and to promote education related to these goals. Scientific Global Talks aligns with this mission.

 

Dr. Linda Sandell, September 7, 2022

“Can We Predict Osteoarthritis? Genetics and Healing in Mice and Humans”

Professor of Orthopaedic Surgery and of Cell Biology and Physiology at Washington University School of Medicine, Dr. Sandell's in-person talk highlights her work using healing and non-healing mice to predict osteoarthritis after injury in humans.

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Dr. Mohit Kapoor, October 5, 2022

"Multi-omics Approach to Understand Osteoarthritis Pathogenesis"

In this talk, Dr. Kapoor will share the utility of multi-omics technologies using human OA biospecimens and pre-clinical models to understand the complex pathophysiology of OA.

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Dr. Karin Allenspach, January 25, 2023

"Organoids in Dogs and Cats – New Tools for Novel Treatments"

Since organoids derived from adult stem cells can be cultured from any epithelial tissue and their cancers, this technology holds vast potential for disease modelling in canines and felines. In this seminar, we will discuss pertinent applications of these technologies and show how organoids from companion animals could revolutionize the approach to many diseases frequently seen in clinical practice.

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Dr. Kenneth Simpson, March 22, 2023

"Intestinal Dysbiosis as a Therapeutic Target"

Recent studies have determined that Adherent and Invasive E. coli (AIEC) linked to Crohn’s disease can utilize mucosal metabolites for growth, energy, stress resistance and virulence. From a clinical perspective these MCP-related metabolic pathways could serve as novel targets for therapeutic intervention against AIEC and E. coli-associated dysbiosis.

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Dr. Ephron Rosenzweig, May 17, 2023

"Neural Stem Cell Grafts for Repair of Spinal Cord Injury"

For the past thirteen years, our group has been grafting NSCs into lesion sites in rodents and in clinically-relevant large animal models of SCI. I will describe how we have improved electrophysiological and functional outcomes after even severe SCI. I will also describe our more recent work, which further characterizes mechanisms underlying neuronal relay circuit formation, with the aim of optimizing functional improvement after SCI and bringing this treatment to human clinical trials.

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