Chris Vaaga
Assistant Professor Biomedical SciencesAbout Chris
The Vaaga lab is interested in understanding the cells, synapses, and circuits underlying ethologically relevant behaviors and elucidating the neural mechanisms by which circuits generate behavioral flexibility. To approach these questions, the lab primarily studies defensive behaviors, which are evolutionarily conserved behavioral responses to predator threats in the environment. Importantly, such defensive behaviors are innate, meaning they do not require previous associative learning to be expressed, and yet are remarkably flexible to generate ethologically appropriate behavioral strategies.
To address these questions, the lab employs integrative electrophysiological approaches, combining in vitro electrophysiology, optogenetic/chemogenetic circuit manipulation, in vivo electrophysiological and optical imaging techniques, and behavioral analysis to study the neural circuits responsible for generating innate defensive behaviors. The lab is particularly interested in elucidating cellular motifs within midbrain periaqueductal gray as well as exploring the underappreciated role of the cerebellum in modulating defensive circuits, and ultimately, behavior.
Scientific Mission Statement:
To use integrative physiological approaches to understand how neural circuit activity contributes to the generation of ethologically relevant behaviors. To understand neural circuit function from biophysics to behavior.
Training Mission Statement:
To provide impactful scientific mentorship to train the next generation of scientists to think critically about the world around them. To develop and foster scientific curiosity and innovative data-driven problem-solving approaches.
Mentorship Philosophy:
As a mentor, my philosophy is rooted in creating a supportive environment where all individuals from all backgrounds can thrive personally, professionally, and scientifically. I prioritize intentional, individualized mentorship, understanding that each trainee brings a unique set of experiences, needs, and aspirations. I prioritize creating a laboratory culture that embraces different perspectives, encourages open and honest communication, and ensures all voices are heard and respected.