clinical trials

With help from pet participants, clinical trials help doctors in the medical and veterinary fields discover disease prevention methods and find new ways to improve detection, diagnosis, and treatment of animal illnesses, all while enhancing the quality of care each patient receives.

Select a clinical trial to learn more about specific research goals and to understand what is in store for you and your pet if you choose to participate. All animal participants receive compassionate care throughout their treatment period.

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A Lasting Legacy: Samples collected from a pet after death to study diseases of aging euthanasia December 31, 2040 Biomarker research in aging dogs (BioRAD): A brain aging study in dogs healthy December 31, 2030 Biorepository and advanced research in brain cancer (BARC) brain tumor December 31, 2030 CAR T cell and verdinexor therapy for treatment of brain cancer in dogs glioma tumor December 31, 2028 CAR T cell immunotherapy for treatment of metastatic osteosarcoma in dogs osteosarcoma Clinical characteristics and long-term outcome in cats diagnosed with a ductal plate malformation ductal plate malformation January 31, 2040 Clinical characteristics and long-term outcome in dogs diagnosed with a ductal plate malformation ductal plate malformation May 1, 2034 Clinical Testing of Canine T cells Engineered to Target Osteosarcoma and Soft Tissue Sarcoma in Combination with Oral Immunotherapy soft tissue sarcoma Combination radiation therapy and gilvetmab for the treatment of mast cell tumors in dogs mast cell tumor Combination therapy with gilvetmab and toceranib in dogs with mast cell tumors mast cell tumor Combination trametinib and sapanisertib for canine malignant neoplasia neoplasia COTC 031: Safety evaluation of three forms of an anti-CTLA-4 monoclonal antibody in tumor-bearing pet dogs solid tumor COTC033: Repurposing vaccine immunity to treat cancers, validation in canine patients neoplasia Cryotherapy for canine mast cell tumors mast cell tumor Dual energy CT to assess bone mineral density in dogs with osteosarcoma undergoing stereotactic body radiation therapy osteosarcoma Evaluating adaptation time in dogs undergoing limb amputation osteosarcoma Evaluation of a therapeutic diet on recurrence of feline idiopathic cystitis (FIC) feline idiopathic cystitis June 30, 2027 Expediated carboplatin for treatment of osteosarcoma in dogs osteosarcoma Feline GI Cancer Core inflammatory bowel disease Immunotherapy for the treatment of corneolimbal squamous cell carcinoma in the horse corneolimbal squamous cell carcinoma July 1, 2025 Immunotherapy for the treatment of genital squamous cell carcinoma in the horse squamous cell carcinoma June 1, 2026 Immunotherapy for treatment of periocular sarcoids in the horse periocular sarcoids July 1, 2025 Intramuscular triamcinolone (IMTA) trial osteoarthritis Lattice radiation therapy’s effect on the immune response in canine sinonasal carcinoma sinonasal carcinoma Local immune response to radiation therapy and combined myeloid cell targeted therapy in a dog model of sinonasal carcinoma sinonasal carcinoma Low-dose radiation therapy in dogs with elbow osteoarthritis osteoarthritis Non-surgical chemotherapy treatment for canine brain tumors brain tumor December 31, 2030 Nonsurgical chemotherapy (verdinexor) treatment for canine brain tumors glioma December 31, 2030 Novel therapy with LSD-1 inhibitor for cats with oral squamous cell carcinoma oral squamous cell carcinoma Observational study of a novel canine cancer diet soft tissue sarcoma Oral melanoma study in dogs oral melanoma Palliative radiation therapy with or without bisphosphonates or carboplatin for dogs with osteosarcoma osteosarcoma Pharmacokinetics of compounded chlorambucil in cats with cancer small cell lymphoma Prostride clinical trial lameness June 1, 2026 Single-dose plasma pharmacokinetic analysis of targeted anticancer agents in tumor-bearing dogs malignant neoplasia SOCH (Scout Out Hemangiosarcoma) Study Canine Splenic Hemangiosarcoma Stress protein inhibitor (SPI) for glioma treatment glioma tumor December 31, 2030 Testing of deceased animals for staggering disease staggering disease March 31, 2027 The Dog Aging Project: Test of rapamycin in aging dogs aging December 31, 2028 The effect of intravenous carboplatin on pain control in dogs with appendicular osteosarcoma osteosarcoma The use of cannabidiol (CBD) as an alternative to standard anticonvulsant therapy in dogs with idiopathic epilepsy epilepsy January 31, 2026 TRAC study: Investigating the effect of trazodone, rapamycin, and cannabidiol on cognitive dysfunction in dogs cognitive dysfunction December 31, 2030

clinical trials in the news view all

New York Observer: 10 Best CBD Oil for Dogs: Best for Anxiety, Pain, & Arthritis

This brings us to a groundbreaking study from Colorado State University, where dogs with idiopathic epilepsy (epilepsy with no known cause) were split into CBD and placebo groups.

Clinical trial leads to surprise diagnosis: “We have to consider the whole patient”

Gina Barrios enrolled her dog, Charlie, in a CSU Veterinary Teaching Hospital clinical trial to help other dogs. The trial not only treated his arthritis but also discovered a hidden tumor, leading to successful surgery and a promising prognosis.

A CSU-led study treating canine trauma patients might one day aid soldiers on the battlefield

The study aimed to determine the effectiveness of administering freeze-dried blood products to canine trauma patients.

Business Wire: Calviri Completes Enrollment of 800 Dogs in a Preventative Cancer Vaccine Trial

The double-blinded trial is testing Calviri’s vaccine aimed at broadly preventing cancers in dogs. It is being conducted at three leading canine oncology centers – the Flint Animal Cancer Center at CSU, the School of Veterinary Medicine at University of Wisconsin-Madison and the University of California-Davis School of Veterinary Medicine.