clinical trials

With help from pet participants, clinical trials help doctors in the medical and veterinary fields discover disease prevention methods and find new ways to improve detection, diagnosis, and treatment of animal illnesses, all while enhancing the quality of care each patient receives.

Select a clinical trial to learn more about specific research goals and to understand what is in store for you and your pet if you choose to participate. All animal participants receive compassionate care throughout their treatment period.

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A Lasting Legacy: Samples collected from a pet after death to study diseases of aging euthanasia December 31, 2040 Allogeneic stromal cells for canine osteoarthritis osteoarthritis November 1, 2026 Asparaginase, procarbazine, prednisone, and lomustine (APPL) for canine multicentric lymphoma canine lymphoma Biorepository and advanced research in brain cancer (BARC) brain tumor December 31, 2030 Brain health study: Biomarker research in aging dogs (BioRAD) healthy December 31, 2030 CAR T cell and verdinexor therapy for treatment of brain cancer in dogs glioma tumor December 31, 2028 CAR T cell immunotherapy for treatment of metastatic osteosarcoma in dogs osteosarcoma Clinical characteristics and long-term outcome in cats diagnosed with a ductal plate malformation ductal plate malformation January 31, 2040 Clinical characteristics and long-term outcome in dogs diagnosed with a ductal plate malformation ductal plate malformation May 1, 2034 Clinical Testing of Canine T cells Engineered to Target Osteosarcoma and Soft Tissue Sarcoma in Combination with Oral Immunotherapy soft tissue sarcoma Combination of lapatinib and fractionated radiation therapy for dogs with transitional cell carcinoma bladder tumor Combination therapy with gilvetmab and toceranib in dogs with mast cell tumors mast cell tumor Contrast-enhanced computed tomography of presumed insulinoma in ferrets insulinoma September 30, 2030 COTC027: Preclinical Comparison of Two Hypomethylating Nucleosides in Tumor-Bearing Dogs solid tumor COTC033: Repurposing vaccine immunity to treat cancers, validation in canine patients neoplasia Diet and seizures study epilepsy December 31, 2030 Dual energy CT to assess bone mineral density in dogs with osteosarcoma undergoing stereotactic body radiation therapy osteosarcoma Evaluating adaptation time in dogs undergoing limb amputation osteosarcoma Evaluation of intra-muscular injection of triamcinolone on naturally occurring osteoarthritis-associated pain in dogs (IMTA) osteoarthritis May 31, 2026 Expediated carboplatin for treatment of osteosarcoma in dogs osteosarcoma Feline GI Cancer Core inflammatory bowel disease Immunotherapy for the treatment of eyelid and corneolimbal squamous cell carcinoma in the horse squamous cell carcinoma May 1, 2027 Immunotherapy for the treatment of genital squamous cell carcinoma in the horse squamous cell carcinoma June 1, 2026 Immunotherapy for treatment of corneolimbal squamous cell carcinoma in the horse ocular squamous cell carcinoma July 1, 2026 Investigating the efficacy of intestinal phosphate binders and subcutaneous fluid therapy in the management of feline chronic kidney disease chronic kidney disease February 10, 2027 Low-dose radiation therapy in dogs with elbow osteoarthritis osteoarthritis May 31, 2026 Minimally invasive sentinel lymph node mapping for canine apocrine gland anal sac adenocarcinoma (AGASACA) carcinoma Non-surgical chemotherapy treatment for canine brain tumors brain tumor December 31, 2030 Nonsurgical chemotherapy (verdinexor) treatment for canine brain tumors glioma December 31, 2030 Observational study of a novel canine cancer diet soft tissue sarcoma Oral melanoma study in dogs oral melanoma Prostride clinical trial lameness June 1, 2026 SOCH (Scout Out Hemangiosarcoma) Study Canine Splenic Hemangiosarcoma Stress protein inhibitor (SPI) for glioma treatment glioma tumor December 31, 2030 Testing of deceased animals for staggering disease staggering disease March 31, 2027 The Dog Aging Project: Test of rapamycin in aging dogs aging December 31, 2028 The use of cannabidiol (CBD) as an alternative to standard anticonvulsant therapy in dogs with idiopathic epilepsy epilepsy January 31, 2026 TRAC study: Investigating the effect of trazodone, rapamycin, and cannabidiol on cognitive dysfunction in dogs cognitive dysfunction December 31, 2030

clinical trials in the news view all

New York Observer: 10 Best CBD Oil for Dogs: Best for Anxiety, Pain, & Arthritis

This brings us to a groundbreaking study from Colorado State University, where dogs with idiopathic epilepsy (epilepsy with no known cause) were split into CBD and placebo groups.

Clinical trial leads to surprise diagnosis: “We have to consider the whole patient”

Gina Barrios enrolled her dog, Charlie, in a CSU Veterinary Teaching Hospital clinical trial to help other dogs. The trial not only treated his arthritis but also discovered a hidden tumor, leading to successful surgery and a promising prognosis.

A CSU-led study treating canine trauma patients might one day aid soldiers on the battlefield

The study aimed to determine the effectiveness of administering freeze-dried blood products to canine trauma patients.

Business Wire: Calviri Completes Enrollment of 800 Dogs in a Preventative Cancer Vaccine Trial

The double-blinded trial is testing Calviri’s vaccine aimed at broadly preventing cancers in dogs. It is being conducted at three leading canine oncology centers – the Flint Animal Cancer Center at CSU, the School of Veterinary Medicine at University of Wisconsin-Madison and the University of California-Davis School of Veterinary Medicine.