clinical trials

With help from pet participants, clinical trials help doctors in the medical and veterinary fields discover disease prevention methods and find new ways to improve detection, diagnosis, ​and treatment of animal illnesses, all while enhancing the quality of care each patient receives.

Select a clinical trial to learn more about specific research goals and to understand what is in store for you and your pet if you choose to participate. All animal participants receive compassionate care throughout their treatment period.

trial name conditions enrollment ends
Adjuvant immunotherapy combination with losartan/toceranib/ladarixin for non-metastatic osteosarcoma osteosarcoma Biomarker research in aging dogs (BioRAD): A brain aging study in dogs healthy December 31, 2030 Brain tumor biobanking brain tumor December 31, 2030 Canine physical orthopedic performances (CPOP) osteoarthritis January 1, 2025 Canine traumatic injury stabilization (BodeVet/LoVLETR) penetrating trauma Clinical characteristics and long-term outcome in dogs diagnosed with a ductal plate malformation ductal plate malformation May 1, 2034 Combination radiation therapy and gilvetmab for the treatment of mast cell tumors in dogs mast cell tumor Combination therapy with gilvetmab and toceranib in dogs with mast cell tumors mast cell tumor Combination trametinib and sapanisertib for canine malignant neoplasia neoplasia Comparison of oral flunixin, acetaminophen, or a flunixin-acetaminophen combination for the treatment of ocular pain in the horse painful eye conditions July 1, 2025 COTC027: Preclinical Comparison of Two Hypomethylating Nucleosides in Tumor-Bearing Dogs solid tumor COTC031: Novel immune therapy for dogs with lymphoma or solid tumors solid tumor COTC033: Repurposing vaccine immunity to treat cancers, validation in canine patients neoplasia Dogs scheduled to receive doxorubicin chemotherapy multiple tumor types Evaluating adaptation time in dogs undergoing limb amputation osteosarcoma Feline GI Cancer Core inflammatory bowel disease Focal adhesion kinase inhibition to improve losartan-toceranib immunotherapy in canine metastatic osteosarcoma osteosarcoma Freeze-dried conditioned serum clinical trial lameness December 31, 2024 Immunotherapy for the treatment of corneolimbal squamous cell carcinoma in the horse corneolimbal squamous cell carcinoma July 1, 2025 Intramuscular triamcinolone (IMTA) trial osteoarthritis Ketamine trial osteoarthritis Lattice radiation therapy’s effect on the immune response in canine sinonasal carcinoma sinonasal carcinoma Librela trial osteoarthritis Local immune response to radiation therapy and combined myeloid cell targeted therapy in a dog model of sinonasal carcinoma sinonasal carcinoma Low-dose radiation therapy in dogs with elbow osteoarthritis osteoarthritis Novel therapy with LSD-1 inhibitor for cats with oral squamous cell carcinoma oral squamous cell carcinoma Oral melanoma study in dogs oral melanoma Palliative radiation therapy with or without bisphosphonates or carboplatin for dogs with osteosarcoma osteosarcoma Pharmacokinetics of compounded chlorambucil in cats with cancer small cell lymphoma Phase I clinical trial of NIH 972 in dogs with spontaneously occurring sarcomas sarcoma Phase-1 evaluation of vismodegib plus carboplatin in dogs with spontaneous osteosarcoma osteosarcoma Prostride clinical trial lameness December 31, 2024 The effect of intravenous carboplatin on pain control in dogs with appendicular osteosarcoma osteosarcoma TRAC study: Investigating the effect of trazodone, rapamycin, and cannabidiol on cognitive dysfunction in dogs cognitive dysfunction December 31, 2030 Treatment of periocular sarcoids in the horse using immunotherapy periocular sarcoids September 3, 2024 Use of superficial radiation therapy for treatment of eyelid squamous cell carcinoma in the horse eyelid squamous cell carcinoma August 1, 2024

clinical trials in the news view all

Business Wire: Calviri Completes Enrollment of 800 Dogs in a Preventative Cancer Vaccine Trial

The double-blinded trial is testing Calviri’s vaccine aimed at broadly preventing cancers in dogs. It is being conducted at three leading canine oncology centers – the Flint Animal Cancer Center at CSU, the School of Veterinary Medicine at University of Wisconsin-Madison and the University of California-Davis School of Veterinary Medicine.

University of Colorado Cancer Center: Growing Evidence Shows Increasing Overlaps Between Human and Companion Animal Cancer Research

This trial is one of many examples of not just the collaboration and partnership between CU Cancer Center members around the state, but the overlaps between humans and companion animals, or non-working animals, and the growing body of research showing how one can inform the other.

Your healthy dog can help vets understand how dogs breathe in emergencies

The Arterial Blood Gas at Altitude Study at the Colorado State University James L. Voss Veterinary Teaching Hospital is looking for healthy dogs, especially brachycephalic (short-muzzled, flat-faced) breeds⁠ — English bulldogs, French bulldogs, and pugs ⁠— to participate in this research that will show veterinarians if dogs breathe differently in high altitude environments.

Clinical trials benefit animals and humans

May 20 is international Clinical Trials Day. At Colorado State University, researchers conduct hundreds of clinical trials that yield important insights for human and animal health.