Contrast-enhanced computed tomography of presumed insulinoma in ferrets
Insulinoma is one of the most common neoplastic diseases in ferrets and accounts for up to 25% of neoplasms. The aim of this prospective study is to establish a contrast-enhanced, dynamic perfusion computed tomography protocol for imaging of the abdomen in ferrets with presumed insulinoma. Eight prospectively enrolled ferrets with presumed pancreatic insulinoma that meet inclusion criteria will undergo contrast-enhanced dynamic perfusion computed tomography of the abdomen under sedation followed by a delayed full-body scan. The goal is to describe the contrast-enhanced computed tomography imaging characteristics of presumed pancreatic insulinoma and suspected metastases in ferrets. Safely accessible suspected metastases will be aspirated via ultrasound guidance with cytological evaluation.
The study will cover the cost of whole-body CT with intravenous contrast administration, intravenous catheter placement, focal ultrasound of the pancreas, ultrasound-guided FNAs and cytology, and outpatient monitoring. Owners will be responsible for cost associated with physical exam/consultation, sedation/general anesthesia, blood work, and any additional diagnostics or treatment.
condition(s)
eligibility information
Inclusion criteria for suspected insulinoma:
- History of lethargy, seizures, pelvic limb weakness, and/or pawing at the mouth
- Clinical signs of tremors, stargazing, ataxia, teeth grinding, seizing, and/or coma
- Physical exam findings of mental dullness, pelvic limb weakness, ptyalism
- Blood glucose measurement of less than 70 mg/dL
Enrollment Deadline
Enrollment ends September 30, 2030
contact information
To enroll in this trial, schedule an appointment with CSU’s Avian, Exotic, and Zoological Medicine service.
Patients presenting through Small Animal Emergency and Urgent Care can be transferred to Avian, Exotic, and Zoological Medicine for diagnostics and enrollment in the study.
