Christine Olver
Faculty
Microbiology, Immunology, and Pathology
About Christine
Dr. Olver is Professor of Clinical Pathology. Her research interests include: (1) Red blood cell regeneration and reticulocyte maturation: reticulocytes mature into erythrocytes through a series of secretion pathways, including exosomal secretion pathways. Through proteomic and standard biochemical analysis, this work characterizes the molecular mechanism of exosome biogenesis. In the horse, transferrin receptor expression in serum exosomes is upregulated in a model of regenerative anemia. (2) Diagnostic uses of plasma exosomes: Exosomes, subcellular particles secreted by cells into the circulation, provide a snapshot of cellular activity in distant sites, for example in the diagnosis of canine osteosarcoma.
Education
BS, University of North Carolina-Chapel Hill, 1983PhD, The Ohio State University, 1994DVM, The Ohio State University, 1987
Certifications
Diplomate, Clinical Pathology
American College of Veterinary Pathology
Publications
Comparison of methods for albumin and immunoglobulin depletion from equine
serum.
Christine S. Olver, Teckla L. Webb, Lindsey J. Long, Hataichanok Scherman, Jessica E. Prenni
Accepted Veterinary Clinical Pathology, in revision processCloning and tissue expression of the equine transferrin receptor: progress toward
quantifying a regenerative response in the horse
Teckla L. Webb, Robert C. Burnett1, Anne C. Avery, Christine S. Olver
Submitted to Veterinary Clinical Pathology
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