Brad Borlee

Microbiology, Immunology, and Pathology

About Brad

Dr. Borlee is an Associate Professor of Bacteriology and Boettcher Investigator in the Department of Microbiology, Immunology, and Pathology within the College of Veterinary Medicine and Biomedical Sciences. He was previously a Senior Fellow in the Department of Microbiology at the University of Washington, School of Medicine (Seattle, WA), and earned his Ph.D. conducting microbiology research at the University of Wisconsin (Madison, WI). Highlights of his research career include the pioneering construction of metagenomic libraries to study antibiotic resistance and identification of novel biomolecules from unculturable bacteria. In addition, Dr. Borlee has patented quorum-sensing inhibitors for the development of anti-virulence drug leads. Dr. Borlee’s discovery of a biofilm-induced bacterial adhesin that binds exopolysaccharides and reinforces biofilm structural integrity has been further developed by him into a c-di-GMP biosensor to identify and evaluate antibiofilm therapeutics.


PhD, University of Wisconsin-Madison, 2006BS, University of Wisconsin-Madison, 1998

Research Specialty

Pseudomonas aeruginosa, Staphylococcus aureus, Burkholderia pseudomallei, Burkholderia mallei, Francisella tularensis, Mycobacterium bovisDr. Borlee maintains three laboratories in the Infectious Disease Research Center at CSU that are focused on the study of biofilm-associated infections.With collaborators at CSU, Dr. Borlee’s research group has developed multiple models to study biofilm-associated infections in animal models of disease to evaluate therapeutic efficacy.