Juan Lucas Argueso

Professor Environmental and Radiological Health Sciences


(970) 491-3681

About Juan Lucas

Dr. Argueso's main interests include: - Structural genomic variation - Molecular mechanisms of genetic recombination - Effects of environmental exposure on gene copy number variation (CNV) - Phenotypic consequences of chromosomal rearrangements - Graduate Education, Research Mentoring, Enhancement of STEM workforce diversity


PostDoc - Genome Stability, Duke University Medical Center, 2010Ph.D. - Genetics and Development, Cornell University, 2004M.S. - Genetics and Plant Breeding, University of Sao Paulo, Brazil, 1997B.S. - Agronomic Engineering, University of Sao Paulo, Brazil, 1995


Punctuated aneuploidization of the budding yeast genome. Heasley LR, Watson RA, Argueso JL. Genetics. 2020 216:43-50.Controlled reduction of genomic heterozygosity in an industrial yeast strain reveals wide cryptic phenotypic variation. Sampaio NMV, Watson RA, Argueso JL. Frontiers in Genetics. 2019 10:782.A case study of genomic instability in an industrial strain of Saccharomyces cerevisiae. Rodrigues-Prause A, Sampaio NMV, Gurol TM, Aguirre GM, Sedam HNC, Chapman MJ, Malc EP, Ajith VP, Chakraborty P, Tizei PA, Pereira GAG, Mieczkowski PA, Nishant KT, Argueso JL. Genes Genomes Genetics G3. 2018 8:3703-3713.Stimulation of chromosomal rearrangements by ribonucleotides. Conover HN, Lujan SA, Chapman MJ, Cornelio DA, Sharif R, Williams JS, Clark AB, Camilo F, Kunkel TA, Argueso JL. Genetics. 2015 201:951-61.Gene copy-number variation in haploid and diploid strains of the yeast Saccharomyces cerevisiae. Zhang H, Zeidler AF, Song W, Puccia CM, Malc E, Greenwell PW, Mieczkowski PA, Petes TD, Argueso JL. Genetics. 2013 193:785-801.Genome structure of a Saccharomyces cerevisiae strain widely used in bioethanol production. Argueso JL, Carazzolle MF, Mieczkowski PA, Duarte FM, Netto OV, Missawa SK, Galzerani F, Costa GG, Vidal RO, Noronha MF, Dominska M, Andrietta MG, Andrietta SR, Cunha AF, Gomes LH, Tavares FC, Alcarde AR, Dietrich FS, McCusker JH, Petes TD, Pereira GA. Genome Research. 2009 19:2258-70.Double-strand breaks associated with repetitive DNA can reshape the genome. Argueso JL, Westmoreland J, Mieczkowski PA, Gawel M, Petes TD, Resnick MA. Proceedings of the National Academy of Sciences USA. 2008 105:11845-50.Competing crossover pathways act during meiosis in Saccharomyces cerevisiae. Argueso JL, Wanat J, Gemici Z, Alani E. Genetics. 2004 168:1805-16.