George Seidel JrBiomedical Sciences
W129 Arblgeorge.email@example.com (970) 491-5287
Since 1965, I have taught in dozens of courses at Cornell University, Harvard Medical School, and Colorado State University concerning biomedical sciences and animal sciences, mostly specializing in reproductive physiology. However, I technically retired in 2011, and although I have been rehired on a part-time basis, my teaching is now limited to occasional guest lectures, and my active involvement in research has decreased as well. I no longer take new graduate and postdoctoral students as major advisor. In recent years, my main research focus has been in vitro fertilization and culture of mammalian embryos, including the related areas of oocyte maturation, micromanipulation, and cryopreservation of embryos and oocytes, both conventionally and via vitrification. We also developed systems for cryopreservation that have no components of animal origin, such as serum albumin, to decrease chances of spreading viral diseases. Most of this research is with cattle and horses. We have found that oxidizing NADPH with phenazine ethosulfate decreases lipid droplets markedly in in vitro-produced bovine embryos. We have also found that fructose is superior to glucose for culturing bovine embryos in vitro, and determined that capacitation of equine sperm occurs more readily when polyvinyl alcohol rather than serum albumin is the macromolecule in the fertilization medium. Another project concerned improving the process of sexing sperm, particularly in keeping sperm healthy between semen collection and actual sexing. We continue to do considerable experimentation on practical methods of synchronizing ovulation of fertile bovine oocytes using cattle on cooperating and University ranches. We recently demonstrated beef could be produced with ~30% less inputs such as feed, water, and energy , and similarly ~30% fewer waste products such as methane and carbon dioxide, by breeding heifers with sexed semen so that each female replaces herself and is fattened and slaughtered after having one calf. This system eliminates the mature beef cow herd, resulting in the increased efficiency because all animals in the herd are growing at all times.