Angelo Izzo

Faculty Microbiology, Immunology, and Pathology

C220 Micro

970-491-4350

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About Angelo

Dr. Izzo is Associate Professor of Mycobacterial Immunology. His laboratory develops protocols for testing novel M. Tb vaccine candidates in rodent low dose aerosol experimental models. Mouse and the guinea pig models are used to dissect the immunological and pathological responses associated with vaccines, including investigations of innate immune response in induction of protective immune responses to M. Tb. His lab currently evaluates M. Tb pathogenicity in inbred vs outbred guinea pig strains, and evaluates the relationship of clinical parameters (ie body temperature, arterial blood gas) to disease progression.

Education

BS, Adelaide Uinversity, 1982PhD, Adelaide University, 1992

Publications

Taylor J.L., Wieczorek A., Keyser A.R., Grover A., Karls R.K., Bielefeldt-Ohmann H., Dobos K.M. and Izzo A.A. (2012) HspX-mediated protection against pulmonary Mycobacterium tuberculosis is dependent on its ability to chaperone a mycobacterial molecule Immunology and Cell Biology 90:945-954 Grover A. & A.A. Izzo (2012) BAT3 regulates Mycobacterium tuberculosis protein ESAT-6-mediated apoptosis of macrophages PLoS One 7(7):e40836. Epub 2012 Jul 13 Cayabyab M.J., L. Qin, S.S. Kashino, A. Izzo, A. Campos-Neto. (2013) An unbiased peptide-wide discovery approach to select Mycobacterium tuberculosis antigens that target CD8+ T cell response during infection Vaccine Aug 9. doi:pii: S0264-410X(13)01068-2

                
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