Angelo Izzo

Dr. Izzo is Associate Professor of Mycobacterial Immunology. His laboratory develops protocols for testing novel M. Tb vaccine candidates in rodent low dose aerosol experimental models. Mouse and the guinea pig models are used to dissect the immunological and pathological responses associated with vaccines, including investigations of innate immune response in induction of protective immune responses to M. Tb. His lab currently evaluates M. Tb pathogenicity in inbred vs outbred guinea pig strains, and evaluates the relationship of clinical parameters (ie body temperature, arterial blood gas) to disease progression.